Interactions of living cells with radiation products and oxidative environments

Dr Kevin McGuigan

Dept. of Physiology and Medical Physics, The Royal College of Surgeons in Ireland, 123 St. Stephen's Green, Dublin 2, Ireland
Tel: +353 (0)1 4022207 (office), +353 (0)1 4022135 (secretary)
Fax:+353 (0)1 4022168


Research interests
The primary topic of research is the mechanism of cell death and cell repair for biological pathogens in oxidative aqueous environments. Historically the research has centred on photobiology and in particular solar and photocatalytic inactivation of waterborne pathogens for use in developing countries. More recently our attention has turned to the effects of radiation products on living cells.

Relevant publications

Refereed Publications
1. Kehoe SC, Barer MR, Devlin L, McGuigan KG.
Batch process solar disinfection is an efficient means of disinfecting drinking water contaminated with Shigella dysenteriae Type I.
In Press. Lett Appl. Microbiol. LAM-2003-1149 (accepted Feb 2004)

2. Conroy RM, Elmore-Meegan M, Joyce TM, McGuigan KG, Barnes J.
Use of solar disinfection protects children under 6 years from cholera.
Arch Dis Child, 2001:85, 293-295.

3. Wegelin M, Canonica A, Alder A, Suter M, Bucheli TD, Haefliger OP, Zenobi R, McGuigan KG, Kelly MT, Ibrahim P, Larroque M.
Does sunlight change the material and content of PET bottles?
J Water SRT - Aqua 2001;50, 125-135

4. Kehoe SC, Joyce TM, Ibrahim P, Gillespie JB, Shahar RA, McGuigan KG.
Effect of agitation, turbidity, aluminium foil reflectors and volume on inactivation efficiency of batch-process solar disinfectors.
Water Research 2001;35:4,1061-1065.

5. Smith RJ, Kehoe SC, McGuigan KG, Barer MR.
Effects of simulated solar disinfection on infectivity of Salmonella typhimurium.
Lett Appl Microbiol 2000; 31: 4, 284-288.

6. K. G. McGuigan, E. McGlynn, F. O'Cairbre, J. Love, M. O. Henry.
Piezo-spectroscopic induced perturbations for defects in cubic crystals under uniaxial stress applied along arbitrary low symmetry crystal directions.
J. Phys.C. 2000; 12:31, 7055-7068.

7. Conroy RM, Elmore-Meegan M, Joyce TM, McGuigan KG, Barnes J.
Use of sunlight to reduce risk of diarrhoeal disease in Maasai children. An update.
Arch Dis Child, 1999; 81: 337-338.

Submitted for refereed publication
1. Lonnen J, Kilvington S, Kehoe SC, Al-Touati F, McGuigan KG.
Solar disinfection and solar photocatalytic disinfection of protozoan, fungal and bacterial resistant pathogens in drinking water.
Manuscript submitted for publication Water Research. (Nov.. 2003).

2. Duffy EF, Al Touati F, Kehoe SC, McLoughlin OA, Gill L, Gernjak W, Oller I, Maldonado MI, Malato S, Cassidy J, Reed RH, McGuigan KG.
A novel TiO2-assisted solar photocatalytic batch-process disinfection reactor for the treatment of biological and chemical contaminants in domestic drinking water in developing countries.
Manuscript submitted for publication in Solar Energy (Nov. 2003).

3. McLoughlin OA, Kehoe SC, McGuigan KG, Duffy EF, Al Touati F, Gernjak W Oller I, Malato S, Gill LW
Solar disinfection of contaminated water: a comparison of three small-scale reactors.
Manuscript submitted for publication in Solar Energy (Nov. 2003).

COST P9 Workings group(s) of interest: WG3 (Chairman)