Reactions of Gaseous Biological Molecules

Prof. Chava Lifshitz

Institute of Chemistry, Hebrew University, Givat Ram, Jerusalem 91904, Israel



Research interests

We are studying reactions of gaseous biological molecules. The molecules are introduced into the gas phase either by laser desorption (LD) or by electrospray ionization (ESI). Bimolecular reactions of protonated and multiply protonated biomolecules (amino acids, amino acid clusters, peptides and proteins) are studied using a fast flow method and quadrupole mass spectrometry. The system is truly thermal and quantitative kinetic information is derived. The interest until now has centered on H/D exchange and multiply hydrogen bonded systems. In a separate experiment, the unimolecular reactions of biological radical cations, amino acids and peptides, are studied using laser ionization, laser excitation, an ion-trapping device and time-of-flight mass spectrometry.

Recent publications

B. G. Reuben, Y. Ritov, O. Geller, M. A. McFarland, A. G. Marshall and C. Lifshitz, Chem. Phys. Lett., 380, 88-94 (2003).

Y. Hu, B. Hadas, M. Davidovitz, B. Balta and C. Lifshitz, J. Phys. Chem. A, 107, 6507-6514 (2003).

COST P9 Workings group(s) of interest: